As part of a probability assessment when DVT or PE is suspectedĢ. When is the D-Dimer indicated in Emergency?ġ. When can the D-Dimer be positive? PATHOLOGICAL

The standard cut-off for venous thromboembolism is 0.5mg/L FEU or 0.25mg/L DDU. The reporting units used will affect the cut-off. Most contemporary laboratories use high sensitivity assays.ĭ-dimer can be reported as fibrinogen equivalent units (FEU) or d-dimer units (DDU). Check your local institutions guidelines. Furthermore, different laboratories may use different ‘cut-offs’ for what constitutes a positive or negative result.

There are many different D-Dimer assays (qualitative and quantitative) available.ĭifferent types of assay are not standardised and have varying sensitivities and specificities. It is a marker of blood clotting activity.